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Esiclene - Formebolone

Pharmaceutical Name: Formebolone
Chemical structure: 11alpha, 17beta-Dihydroxy-17-methyl-3-oxoandrosta-1,4-dien-2-carboxaldehyde Formyldienolone
Active Life: 24-36 hours
Anabolic/Androgenic Ratio: N/A

Formebolone is an anabolic steroid that is primarily used by competitive bodybuilders for purposes other then its muscle building capabilities. The anabolic and androgenic nature of formebolone is actually quite small (1) and will offer little benefit in these terms other then a small increase in nitrogen retention and protein synthesis (2). However the drug does offer a unique attribute, namely the ability to cause a temporary increase in muscle size by way of localized inflammation and fluid retention in the treated muscles.

Obviously a temporary increase in muscle size due to inflammation will likely only be beneficial to competitive bodybuilders during competitions. There would be little need for it in other athletic areas. However for this small niche, formebolone is quite effective.

With localized inflammation will come muscle discomfort. This is a necessary by-product of formebolone. For this reason a local anaesthetic or painkiller is usually added to the compound, often times being lidocaine. This should make the injection slightly less painful. But some discomfort in the treated muscle will always result.

With the result of the administering formebolone being localized muscle inflammation, it should be apparent that the drug is best suited for use in smaller muscles. The effect of the drug will be far more noticeable and the results more predictable. Use in larger muscle groups can result in an off look being produced, with possibly only portions of the muscle being affected.

Use and Dosing of Formebolon

Due to the desired effect of formebolone being only a temporary one, administration of the drug will take place for relatively short periods of time. This combined with the fact that the compound does create a fairly substantial amount of discomfort in the muscles that it is injected into, and it should be obvious that formebolone users will only want to administer the drug for as long as is necessary to achieve the desired results.

Most users anecdotally report that the maximal benefit of the drug notably the maximum increase in the size of the treated muscle due to irritation is produced within days of the first injection of the drug. For this reason it is unnecessary to administer the drug for longer then ten to fourteen days prior to the day when the maximum effect of the drug is to be realized.

In terms of dosing, most users will find that one to two milligrams of formebolone per muscle injected will be sufficient to produce good results. Of course one will have to experiment with the size of the dosage to not only see how much of the drug is needed to produce adequate results but also how much of the drug can be tolerated by the user.

To maintain the maximum increase in muscle size of the treated areas, injection frequency is important. Due to the active life of formebolone injections every day or every other day should be administered. If they are less frequent the increase in muscle size will begin to decrease and the maximum effect of the drug will not be maintained.

Risks/Side Effects of Formebolone

Formebolone poses few risks for users due to the short duration with which most will choose to administer the drug and the relatively low doses that are needed to achieve the desired result. Beyond the temporary discomfort that will be suffered by the user due to the localized muscle irritation there should be no long term side effects as a result of formebolone use.

As indicated earlier, formebolone is a 17-alpha-alkylated steroid and therefore can be hepatoxic when used in large doses. For those users administering the injectable version of the drug this will not be a concern as the dosage used will not result in any significant strain on the liver. However for those users administering the oral version formebolone, hepatoxicity may be an issue due to the larger doses that have to be administered for a significant benefit to be achieved. Of course this risk can be minimized by administering moderate doses of the compound, running the drug for short periods of time and using supplements to help reduce liver toxicity while while running the drug.

Virilization symptoms are not a concern with the use of formebolone and can be relatively safely used by females. Masculinizing side effects will not result from normal use of this drug.


1. Cerutti S, Forlani A, Galimberti E. Anticatabolic action of formebolone in the castrated rat treated with dexamethasone. Arzneimittelforschung. 1976;26(9):1673-7.

2. Esposito R, Pluvio M, Giordano D. Anabolic agents in kidney disease: the effect of formebolone on protein synthesis in patients with renal insufficiency or nephrosis. Curr Med Res Opin. 1975;3(1):43-5.

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