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Furazabol
Pharmaceutical Name: Furazabol
Chemical structure: 17-alpha-methyl-5-alpha-androsta-2,3-furazan,17b-ol
Molecular Formula: C20H30N2O2
Molecular weight of base: 330.4692
Active Life: approximately 4 hours
Anabolic/Androgenic Ratio (Range): 270-330/73-94
Furazabol is a 17-alpha-alkylated oral steroid that is derived from
dihydrotestosterone (DHT). Interestingly, it also has no 3-keto group, which
is needed for androgenic binding (1). This obviously hinders the androgenic
activity of the compound and thus limits its muscle and strength building
abilities. These are traits shared by Stanozolol. It is for this reason that
Furazabol is most commonly compared to Stanozolol in both their structures and
effects.
For the most part this compound is considered a �pre contest� compound for
bodybuilders. Due to its androgenic effects and lack of estrogenic activity,
users with relatively low body fat should notice a �muscle hardening� effect
when using adequate dosages. Users anecdotally report that there is little to
no water retention when administering the drug, and muscle begins to appear
much denser and harder. This would follow from the lack of aromatization and
androgenic nature of the drug.
However, these effects should also serve as a caution that major gains in
muscle mass or strength are not likely to be experienced with Furazabol. There
is simply not enough androgenic activity to provide these. However, if used
for the specific purpose of enhancing the appearance of the user�s muscle,
Furazabol can be quite beneficial when used in conjunction with other anabolic
compounds.
An interesting and beneficial difference between Furazabol and Stanozolol is
their effects on users� cholesterol levels. While Stanozolol will drive HDL
levels down and LDL level will increase, Furazabol actually improves these. In
animal studies it has been shown that administration of Furazabol increases
levels of plasminogen (2). Plasminogen is a substance found in the fluids of
the body that becomes plasmin when activated which is an enzyme in plasma that
is responsible for the destructuring of blood clotting substances in the body.
This effect resulted in the decrease in plasma fibrinogen levels as well as a
decrease in plasma cholesterol levels. Of course these effects only lasted as
long as administration of the drug continued and quickly dissipated once this
was ceased (2). However for this reason it can be concluded that, at least in
terms of cholesterol health, Furazabol would be a much safer choice than
Stanozolol.
Use/Dosing of Furazabol
In terms of dosing, for inexperienced males users, doses in the range of 30-90
milligrams per day should be sufficient to promote very noticeable gains. Due
to the short active life of the compound, multiple doses a day should be
administered. Three to four would likely be the minimum needed to provide the
users with stable blood concentrations of the drug.
In terms of the appropriate dosage for use by women, 5 to 20 milligrams per
day should be adequate to experience gains in muscle mass and density. As
always however, doses larger than those recommended here have been
experimented with by both males and females. Of course with these increasing
doses come greater risks and likelihood undesirable side effects will be
experienced.
While there have been some studies conducted that have indicated that
Furazabol has little effect on endogenous testosterone production, for the
most part these studies used relatively small doses (3), much smaller than
would be needed to experience any type of muscle building effect. For this
reason, along with the fact that it is unlikely that any male users would
administer Furazabol without running any other type of anabolic steroid(s) in
conjunction with it, the regular post-cycle recovery protocol should be
followed.
Risks/Side Effects of Furazabol
Furazabol can not aromatize and therefore estrogenic side effects are not a
concern with this compound. As well, the drug is relatively mild in terms of
expected androgenic side effects and therefore these should not be a source of
concern for most users. This is also a reason why Furazabol is a relatively
safe choice for women.
The only real cause of concern for most users would be that the compound is
derived from dihydrotestosterone as it relates to (1,4). This of course will
indicate that side effects associated with dihydrotestosterone could become
apparent with use of the drug. Hair loss, acne and prostate enlargement are
all possible side effects that could be encountered when administering the
compound.
Finasteride will usually help in preventing or minimizing the effects of
dihydrotestosterone, but it will not help with this as a result of furazabol.
This is due to the fact that as stated the drug is derived from
dihydrotestosterone and so its androgenic activity will not be increased via
interaction with the 5 alpha reductase enzyme. However these related side
effects should be tolerable if dosages and cycle length are kept within
reasonable limits.
As noted earlier, since the compound is 17-alpha-alkylated liver values will
likely be raised when administering it. For this reason, and the fact that
permanent liver damage is possible, it is recommended that a user limit their
use of the drug to about 4-8 weeks. This moderate length of use should not
result in any serious complications in terms of liver health.
References
1. Kim T, Suh JW, Ryu JC, Chung BC, Park J. Excretion study of
furazabol, an anabolic steroid, in human urine. J Chromatogr B Biomed Appl
1996 Dec 6;687(1):79-83
2. Kumada T, Abiko Y. Enhancement of fibrinolytic and thrombolytic potential
in the rat by treatment with an anabolic steroid, furazabol. Thromb Haemost.
1976 Nov 30;36(2):451-64
3. Ichii S. Changes in the cytoplasmic androgen receptor of rat ventral
prostate after administration of androgens, antiandrogens and anabolic
steroids. Endocrinol Jpn. 1980 Aug;27(4):483-93
4. Gradeen CY, Chan SC, Przybylski PS. Urinary excretion of furazabol
metabolite. J Anal Toxicol. 1990 Mar-Apr;14(2):120-2
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